Ghost of Tsushima is set in Japan in the year 1274. Samurai warriors are the legendary defenders of Japan, until the fearsome Mongol Empire invades the island of Tsushima, wreaking havoc and conquering the local population.

As one of the last surviving samurai, the player will rise from the ashes to fight back. But, honorable tactics won't lead them to victory. They must move beyond their samurai traditions to forge a new way of fighting: the way of the Ghost.